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Paxil in the Third Trimester

Mothers who used Paxil or similar antidepressants after the 20th week of pregnancy are six times more likely to give birth to a baby with persistent pulmonary hypertension of the newborn (PPHN), a serious and potentially deadly circulatory condition. According to research published in the New England Journal of Medicine, the use of antidepressants including Paxil during the third trimester of pregnancy may raise the risk of other respiratory conditions.

Researchers involved with the study analyzed the risk of PPHN prior to and after the 20th week of pregnancy for pregnant women who used antidepressants such as Paxil called selective serotonin reuptake inhibitors (SSRIs). Scientists also looked at the risk of PPHN for mothers who did not use antidepressants during pregnancy, as well as women who used non-SSRI antidepressants.

The study found that women who used antidepressants like Paxil after their 20th week of being pregnant were six times more likely to have a child with PPHN than non-SSRI users. Researchers also found that women who used SSRIs such as Paxil after the 20th week of pregnancy were over 20 times more likely to give birth to a child with PPHN than those who used this class of antidepressants before this point.

The study also speculated that other respiratory problems besides PPHN—including failure to cry, mild respiratory distress and cyanosis—could be caused by the same factors that increase a child’s risk of PPHN due to exposure to Paxil or other SSRI antidepressants.

If you or a loved one used Paxil or another antidepressant during pregnancy and gave birth to a child with PPHN or other birth defects, you may be eligible to file a lawsuit. For a free legal consultation, contact the lawyers at Hissey Kientz, LLP by calling toll-free at 1-866-275-4454, or by filling out the free case evaluation form located on this page.

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